Genetics
Study pinpoints cell that helps liver heal
A type of cell responsible for repairing damaged liver tissue has been uncovered for the first time by scientists.
May 2, 2024
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24
Acute Liver Failure
Diseases, Conditions, Syndromes
Team uncovers social, economic factors influencing acute liver failure in children, and ways to overcome them
Imagine your healthy child gets sick—so sick that you take them to the emergency department. You are shocked to find out that their liver is failing, and they will need a transplant to survive. Studies show that their chances ...
Feb 13, 2024
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0
Pediatrics
Researchers develop clinical tool to predict if a child in acute liver failure will need a transplant
About 50 children are waitlisted for transplants in the U.S. a year due to acute liver failure. Unlike children with chronic liver disease, previously healthy children who develop acute liver failure can suddenly deteriorate. ...
Oct 23, 2023
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6
Diseases, Conditions, Syndromes
Consumer Health: Are you at risk for hepatitis?
Hepatitis is inflammation of the liver. The five main strains of the hepatitis virus are referred to as types A, B, C, D and E. While they all cause liver disease, they differ in geographic prevalence, modes of transmission, ...
Jul 29, 2023
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2
Surgery
Research may speed identification of patients who need liver transplants
Research findings from Rutgers, the University of Michigan, the University of Texas Southwestern, and the Medical University of South Carolina could save lives by enabling faster and more accurate identification of hospitalized ...
Mar 27, 2023
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13
Medications
FDA mandate to limit acetaminophen in acetaminophen-opioid medications associated with reduced serious liver injury
A United States Food and Drug Administration mandate to limit the dosage of acetaminophen in pills that combine acetaminophen and opioid medications is significantly associated with subsequent reductions in serious liver ...
Mar 7, 2023
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18
Diseases, Conditions, Syndromes
Epidemiology, prevention and control of hepatitis A virus infection in the European Union
Hepatitis A is an acute liver disease caused by the hepatitis A virus (HAV) and transmitted via the fecal-oral route through person-to-person transmission and contaminated food or water. While hepatitis A infection is mostly ...
Oct 24, 2022
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4
Medications
Novartis says two children treated with gene therapy died
Two children who received Zolgensma, a gene therapy produced by Swiss drugmaker Novartis to treat spinal muscular atrophy, have died from liver failure, the company said Friday.
Aug 12, 2022
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13
Inflammatory disorders
Update on acute liver inflammation of unknown origin in children
Unexplained cases of acute liver inflammation in children, especially in the United Kingdom (U.K.), were reported earlier this year. In response, the European Reference Network on Hepatological Diseases (ERN RARE-LIVER) conducted ...
Aug 8, 2022
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31
Gastroenterology
Could carbon monoxide foam help fight inflammation?
Carbon monoxide is best known as a potentially deadly gas. However, in small doses it also has beneficial qualities: It has been shown to reduce inflammation and can help stimulate tissue regeneration.
Jun 29, 2022
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51
Acute liver failure is the appearance of severe complications rapidly after the first signs of liver disease (such as jaundice), and indicates that the liver has sustained severe damage (loss of function of 80-90% of liver cells). The complications are hepatic encephalopathy and impaired protein synthesis (as measured by the levels of serum albumin and the prothrombin time in the blood). The 1993 classification defines hyperacute as within 1 week, acute as 8–28 days and subacute as 4–12 weeks. It reflects the fact that the pace of disease evolution strongly influences prognosis. Underlying etiology is the other significant determinant of outcome.
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