Research team reveals how TREM2 genetic mutation affects late-onset Alzheimer's
Researchers led by the University of California, Irvine have discovered how the TREM2 R47H genetic mutation causes certain brain areas to develop abnormal protein clumps, called beta-amyloid plaques, associated with late-onset ...
Aug 6, 2024
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It is not clear whether new Alzheimer's drugs will make a difference at a population level, say researchers
Cambridge researchers have cast doubt on whether new amyloid immunotherapy drugs will have the desired effect of significantly reducing the impact of Alzheimer's disease.
Aug 6, 2024
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Can targeted therapies be applied to patients with Alzheimer's?
Alzheimer's disease, a debilitating brain disorder with limited treatment options, has long challenged researchers. Specifically, researchers have struggled with slowing the buildup of amyloid beta plaques, harmful clumps ...
Aug 3, 2024
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Report suggests nearly half of dementia cases could be prevented or delayed by tackling 14 risk factors
Addressing 14 modifiable risk factors, starting in childhood and continuing throughout life, could prevent or delay nearly half of dementia cases, according to a new report led by UCL researchers.
Aug 3, 2024
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Novel sequencing approaches highlight role of brain gene activity in Alzheimer's disease
Innovative new research has revealed that the activity of different versions of genes expressed in the brain is associated with the accumulation of the protein tau, which is a hallmark of Alzheimer's disease.
Aug 2, 2024
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Mouth and dental care for people with dementia often overlooked, study finds
An England-wide study has found the health of people's mouths and teeth is often overlooked by home care services.
Aug 2, 2024
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Clinical trial finds benefit in taking fish oil for those genetically predisposed to Alzheimer's
A clinical trial at Oregon Health & Science University suggests that a subset of older adults with a genetic predisposition to Alzheimer's disease may benefit from fish oil supplements.
Aug 1, 2024
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With new technique, patient-derived neurons accurately model late-onset Alzheimer's disease
Researchers at Washington University School of Medicine in St. Louis have developed a way to capture the effects of aging in the development of Alzheimer's disease. They devised a method to study aged neurons in the lab without ...
Aug 1, 2024
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Weight-loss drug may slow Alzheimer's decline
A drug prescribed for diabetes and weight loss has been shown to reduce brain shrinkage in Alzheimer's patients by almost 50%.
Aug 1, 2024
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Many dementia cases could be prevented, but far from all: Study
Millions of cases of dementia could be prevented or delayed by reducing a range of risk factors such as smoking or air pollution, according to a major new study, though outside experts warn that such measures can only go ...
Aug 1, 2024
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Wildfire smoke exposure linked with higher dementia risk
The wildfires that are increasing with climate change could harm the future brain health of humanity, a new study suggests.
Aug 1, 2024
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Improving Alzheimer's disease imaging, with fluorescent sensors
Neurotransmitter levels in the brain can indicate brain health and neurodegenerative diseases like Alzheimer's. However, the protective blood-brain barrier (BBB) makes delivering fluorescent sensors that can detect these ...
Jul 31, 2024
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Blood proteins may help to track the pathological progression of Lewy body disease
Early detection of Alzheimer's disease-related changes in Parkinson's disease and dementia with Lewy bodies could be made possible by monitoring the amyloid-β (Aβ) and phosphorylated tau (p-tau) proteins. Researchers at ...
Jul 31, 2024
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Nearly half of dementia cases could be prevented or delayed by tackling 14 risk factors starting in childhood
Addressing 14 modifiable risk factors, starting in childhood and continuing throughout life, could prevent or delay nearly half of dementia cases, even as people around the world live longer and the number of people with ...
Jul 31, 2024
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Public health measures that reduce dementia risk could save up to $5bn, UK study suggests
Public health interventions that tackle dementia risk factors could yield as much as £4bn ($4.9bn USD) in savings in England by reducing dementia rates and helping people to live longer and healthier, finds a new study led ...
Jul 31, 2024
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Eating less processed red meat could cut your odds for dementia
Skip the bacon and those holiday hot dogs: A new study finds eating processed red meats raises your odds for dementia.
Jul 31, 2024
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AI boosts the power of EEGs, enabling neurologists to quickly, precisely pinpoint signs of dementia
Mayo Clinic scientists are using artificial intelligence (AI) and machine learning to analyze electroencephalogram (EEG) tests more quickly and precisely, enabling neurologists to find early signs of dementia among data that ...
Jul 31, 2024
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Accuracy of diagnostic blood tests for Alzheimer's disease varies
Neurologists diagnose cognitive impairment with a clinical exam of memory and thinking skills. To determine whether Alzheimer's disease is the cause of the cognitive impairment, evidence of the specific brain changes that ...
Jul 30, 2024
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Study finds blood biomarkers can indicate dementia risk decades before symptoms
Before the advent of extensive research, Alzheimer's disease was only confidently diagnosed postmortem when medical professionals could observe physical changes in the brain associated with the disease, such as the appearance ...
Jul 30, 2024
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Spatial pattern of pathological changes in the brain can help identify dementia vulnerability early
Findings from a novel study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, suggest that using a specialized diffusion weighted MRI scan to monitor the spatial pattern of individual cortical microstructural ...
Jul 30, 2024
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Blood test 91% accurate at predicting Alzheimer's, outperforming doctors
A new test gauging levels of key proteins in the blood was far more accurate than doctor assessments in spotting Alzheimer's disease in people with early-stage illness.
Jul 29, 2024
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Blood tests for Alzheimer's may be coming to your doctor's office. Here's what to know
New blood tests could help doctors diagnose Alzheimer's disease faster and more accurately, researchers reported Sunday—but some appear to work far better than others.
Jul 29, 2024
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Q&A: Signs that cognitive changes are worrisome — and what you can do about it
Amid ongoing conversations about the United States presidential race, a recurring topic has been the cognitive capacity of candidates and some speculation about "cognitive decline"—but what does this mean in terms of a ...
Jul 29, 2024
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